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The complexity of the tumor microenvironment (TME) impacts therapy responses and the survival of cancer patients. The scope of this thesis is to study the effects of immune modulation on tumor-infiltrating leukocytes, and to explore the TME of urothelial cancer to provide the research society with ...
35 Page(s) / 9625 words USD 30.00Business
The thesis consists of four interconnected studies of various topics in the fields of Latvian dialectology and historical linguistics: (1) apocope and shortening; (2) loss of the present 2nd singular endings '?i and '??; (3) the development of the participle desinences '??jis '??jis; (4) the ??
35 Page(s) / 9625 words USD 30.00Business
Bacterial infections and sepsis are amongst the leading causes of death worldwide. Sepsis is caused by an uncontrolled systemic host response towards an invading pathogen. Due to the engagement of various systems including cellmediated responses, the coagulation and complement cascades, treatment o...
35 Page(s) / 9625 words USD 30.00Business
Vehicles are becoming increasingly automated. Already today vehicles are able to take over and assist the human driver in certain driving tasks, and the scope of technical possibilities is rapidly expanding. However, for the proliferation of AVs to occur, there are several challenges that must firs...
35 Page(s) / 9625 words USD 30.00Business
With the rapid development of batteries for applications like electric vehicles and energy storage devices, it is essential to design and develop batteries with improved safety, long cycle life, and high energy density. To achieve this goal, the development and improvement of solid-state batteries, ...
35 Page(s) / 9625 words USD 30.00Business
This thesis describes the work done by the author during the development of a Large Aperture Array Radar (LAAR) receiver for the EISCAT 3D project. The main focus was on digital beamforming of a bandpass-sampled wide band signal in base-band and the development of a picosecond-level distributed timi...
35 Page(s) / 9625 words USD 30.00Business
The world-wide development of new high-speed rail lines has led to more stringent design requirements for railway bridges. This is mainly due to the fact that a train at high speeds can cause resonance in the bridge superstructure. In order to avoid problems of this kind, it has become essential to...
35 Page(s) / 9625 words USD 30.00Business
The pharmaceutical development process starts with patient populations and their unmet therapeutic needs. Traditional pharmaceutical manufacturing of solid oral dosage forms is based on the strategy of one-size-fits-all. This is problematic, especially for patient populations with high patient-to-pa...
35 Page(s) / 9625 words USD 30.00Business
Background: Sequelae after peripheral facial palsy, which among others include synkinesis, non-functional smile and/or lower lip asymmetry, may be devastating for the patient. Bell’s palsy is the most common form of peripheral facial palsy. Aim: The aim was to study a) frequency and potential predic...
35 Page(s) / 9625 words USD 30.00Business
One major focus of anxiety research in recent years has been the identification of cognitive factors that promote increased vulnerability to anxiety. Cognitive formulations propose that anxiety is characterised by an increased tendency to attend to negatively valenced emotional information, and that...
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