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Polycomb group (PcG) proteins are a group of genome wide silencers that are crucial for many processes during the development. In Drosophila PcG proteins are organised into four different complexes: PRC1, PRC2, PhoRC and PR-DUB. PRC2 consists of four core proteins: Su(z)12, E(z), Esc and Nurf. E(z) ...
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Autoimmune diseases encompass a diverse group of disorders that collectively affect 5% of the population. Despite large clinical variability, autoimmune disorders share a common etiology in that they all develop from immune responses against self. T-cell receptors and antibodies recognize distinct s...
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Breast cancer is one of the most common cancers in women. It is most commonly treated by the surgical removal of the tumour in combination with (neo)-adjuvant therapy (hormone, chemo- or radio- therapy before or after surgery). However, a large number of patients are over treated, with approximately...
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When excavating in an urban environment, the evaluation of the magnitude and distribution of ground movements is an important part of the design process, since excessive movements can damage adjacent buildings and utilities. In order to minimize movement of the surrounding soil, a retaining wall sup...
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Antibiotic resistance has become a global health burden with the number of resistant bacteria continuously increasing. Antibiotic drugs act by being either bactericidal (killing bacteria) or bacteriostatic (inhibiting growth of bacteria). However, these modes of action increase the selective pressur...
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Availability of and access to water and energy are key ingredients for economic and social development. Predictions show that pressure on already limited water and energy resources is expected to increase in many parts of the world as a result of growing populations, rapid urbanization, increasing p...
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With the technological progress of materials science, the palette of colours with which to print on textiles has expanded beyond those with previously known properties and expressions to a new generation, with more advanced functionality and expressive properties. This new range of colours is chara...
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Measuring the economic effects of tourism has always been a high priority for private and public actors in the regional economy (Stabler et al 2009). These estimates provide insights about the generation of sales, jobs, and income associated with tourism, but also support industry officials in the ...
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The importance of studying biological molecules in living organisms can hardly be overstated as they regulate crucial processes in living matter of all kinds. Their ubiquitous nature makes them relevant for disease diagnosis, drug development, and for our fundamental understanding of the complex sy...
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Pharmaceuticals are regularly released into the environment, in particular nonsteroidalanti-inflammatory drugs (NSAIDs) and antibiotics. The measuredconcentrations are relatively low and have therefore been considered to be harmless.However, several pharmaceuticals, including naproxen and atenolol, ...
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