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Tertiary education

Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates

Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrate...

50 Page(s) / 13750 words USD 40.00

Tertiary education

New strategies for multifunctional antibacterial materials

Healthcare-associated infections (HAI) are responsible for significant financial and human costs in healthcare systems. Therefore, a substantial amount of research has been devoted to developing biopolymer-based strategies that prevent bacterial attachment and biofilm formation on surfaces. Gelatin ...

30 Page(s) / 8250 words USD 30.00

Tertiary education

Diet and gut microbiota in cardiometabolic health: Studies from the Danish Diet, Cancer and Health – Next Generations Cohort and the sub-cohort MAX

Cardiometabolic diseases (CMD) are the leading cause of death globally. Diet is a key preventive factor of CMD and a determinant of gut microbiota. Gut microbiota, diet and their interactions have been associated with CMD. In observational studies, diet is measured by self-reported instruments, that...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Automation in forestry : development of unmanned forwarders

For the last 50 year, forestry operations have become more and more mechanized. In modern forestry in Europe two machines are typically used; a harvester that fells, debranches and cross-cuts the trees into logs and a forwarder that transports them to the nearest road. These machines are technically...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Tuning the polylactide hydrolysis rate without introducing new migrants

The possibility to control and tune the hydrolytic degradation rate of polylactide without introducing any new degradation products was investigated by subjecting polylactide with cyclic or linear oligolactic acid additives, and a stereocomplex between the L- and D-enantiomers of polylactide to hydr...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Studies of second coordination sphere effects and metal variations on [FeFe]-hydrogenase mimics

Mitigation of climate change motivates researchers to explore hydrogen as a potential energy carrier. Unfortunately, widespread use of hydrogen as an energy carrier is limited by numerous challenges in its production, including high energy consumption; high economic cost; current reliance on rare me...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Computational Modeling of the Mechanisms and Selectivity of Organophosphate Hydrolases

Computational modeling is becoming an increasingly integral part of (bio)chemistry, providing a powerful complementary view into the dynamics, binding, and reactivity of biochemical systems. In particular, molecular simulations based on multiscale models are now regularly employed in studies of enzy...

50 Page(s) / 13750 words USD 30.00

Tertiary education

All-Photonic Control of Biorelevant Processes using Molecular Photoswitches and Caged Compounds

The development of light-controlled molecular tools for in situ regulation of biological activity holds great promise e.g. for resolving dynamic aspects of cellular signal transduction and to overcome inherent pharmaceutic limitations such as poor drug selectivity. In this thesis, photoswitchable mo...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Diastereomeric Effects in DNA Binding – Biological and Biophysical Studies on Ruthenium Complexes

Organic molecules, such as glucose and amino acids, are most often chiral. This means that their mirror-images are different, in the same way a left and a right hand are different from each other. For example, the DNA double helix in its standard form twists like a right-handed screw. Therefore, whe...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Nano- and Micro-sized Molecularly Imprinted Polymer Particles on Solid Surfaces

Molecularly imprinted polymers (MIPs) are artificial receptors made by imprinting template molecules in a polymer matrix followed by their removal through washing to obtain a specific and selective template cavities. This property of the MIPs have made them a very efficient material for diverse appl...

50 Page(s) / 13750 words USD 30.00

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