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Tertiary education

Extracellular electron transfer features of the Gram-positive bacterium Enterococcus faecalis

Electroactive microorganisms possess the unique ability to transfer electrons to or from a solid phase electron conductor, e.g., electrodes or minerals, through various physiological mechanisms. The processes are commonly known as extracellular electron transfer and broadly harnessed in microbial el...

50 Page(s) / 13750 words USD 40.00

Tertiary education

Protein Dimensions and Interactions at Immune-Cell Contacts

Immune cells, such as B and T cells, fight pathogens infecting the human body. To fulfil this function the immune cells need to form a contact during which different membrane proteins play an important role. A key event in this contact is the interaction between the T-cell receptor (TCR) and an anti...

50 Page(s) / 13750 words USD 40.00

Tertiary education

The physical classroom environment : roles, conceptions, and preferences

The problem addressed in this thesis is that a considerable proportion of students around the world attend school in inadequate facilities, which is detrimental for the students’ learning outcome. The overall objective in this thesis is to develop a methodology, with a novel approach to involve teac...

16 Page(s) / 4400 words USD 20.00

Tertiary education

Investigation of nanoparticle-cell interactions for development of next generation of biocompatible MRI contrast agents

Progress in synthesis technologies and advances in fundamental understanding of materials with low dimensionality has led to the birth of a new scientific field, nanoscience, and to strong expectations of multiple applications of nanomaterials. The physical properties of small particles are unique, ...

1 Page(s) / 275 words USD 20.00

Tertiary education

Microgel Interactions with Peptides and Proteins : Consequence of Peptide and Microgel Properties

Microgels are lightly cross-linked hydrogel particles in the sub-micrometer to micrometer size range with a capacity to drastically change their volume in response to changes in the external environment. Microgels have an ability to bind and store substances such as biomacromolecular drugs, notably ...

50 Page(s) / 13750 words USD 30.00

Tertiary education

Microgels as Carriers for Antimicrobial Peptides : Surface-bound microgels, and factors affecting peptide interactions

With a growing number of multi-resistant bacteria against conventional antibiotics, there is an urgent need to identify new antimicrobial therapeutics. One example that has gained considerable interest is antimicrobial peptides (AMPs). For AMPs to reach their full potential as therapeutics, as well ...

50 Page(s) / 13750 words USD 30.00

Tertiary education

On the phase behaviour of hydrogels : A theory of macroion-induced core/shell equilibrium

Colloidal macroions are known to interact very strongly with oppositely charged polyionic hydrogels. Sometimes this results in a non-uniform distribution of the macroions within the gel, a phenomenon that is not fully understood. This thesis is a summary of four papers on the development of a theory...

50 Page(s) / 13750 words USD 40.00

Tertiary education

Selectivity in NMR and LC-MS Metabolomics : The Importance of Sample Preparation and Separation, and how to Measure Selectivity in LC-MS Metabolomics

Until now, most metabolomics protocols have been optimized towards high sample throughput and high metabolite coverage, parameters considered to be highly important for identifying influenced biological pathways and to generate as many potential biomarkers as possible. From an analytical point of vi...

42 Page(s) / 11550 words USD 40.00

Tertiary education

Drugs and polymers in dissolving solid dispersions : NMR imaging and spectroscopy

The number of poorly water-soluble drug substances in the pharmaceutical pipeline is increasing, and thereby also the need to design effective drug delivery systems providing high bioavailability. One favourable formulation approach is preparation of solid dispersions, where dispersing a poorly wate...

50 Page(s) / 13750 words USD 40.00

Tertiary education

Development of LC-MS/MS Methods for the Analysis of Chiral and Achiral Pharmaceuticals and Metabolites in Aqueous Environmental Matrices

This thesis describes the development of liquid chromatography tandem mass spectrometry (LC-MS/MS) methods for the trace analysis of active pharmaceutical ingredients (APIs) and their metabolites in aqueous environmental matrices. The research was focused on the development of chiral LC-MS/MS method...

50 Page(s) / 13750 words USD 40.00

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